Donor Egg, Surrogacy + Genomics
At ORM we incorporate the latest advances in genomics into all types of patient care, including IVF cycles utilizing donor eggs and/or gestational carriers (surrogates). If you are an intended parent who is using an egg donor and/or gestational carrier, or if you are a gestational carrier, you may wish to learn how you might benefit from reproductive genomics.
Donor Egg, Surrogacy + Genomics
For all intended parents who are using donor eggs to start their families, we offer comprehensive chromosome screening (CCS) on the embryos.
- While chromosome problems are more common in embryos created using the eggs of older women, embryos with extra or missing chromosomes are very common, can occur at any age, and are usually not related to one’s family history or other genetic screening results.
- At ORM we have found that 1 in 4 embryos created from donor eggs (age 21-29) have chromosome abnormalities and will not be able to make a healthy baby. Using CCS to select the best embryos for transfer will in some cases improve the pregnancy rate, decrease the chance of a miscarriage occurring, and reduce the chance of the baby having a chromosomal condition such as Down syndrome.
Did You Know?
At ORM over 80% of our donor egg IVF patients now choose to do CCS with a frozen embryo transfer.
Every one of our current egg donors has undergone genetic screening as part of their application process, including:
- Genetic carrier screening for >100 recessive conditions on the Counsyl test. This screening is significantly more comprehensive than the standard practice of many clinics and agencies. By screening the egg donor and the sperm provider(s) for a large number of conditions, we can decrease the chance of a match in which both are unknowingly carriers of the same rare condition. Because ORM egg donors have all been screened via the Counsyl test before they are active in our database, we can also minimize the chance of surprises occurring after you are matched.
- All ORM egg donor applicants have a 30-minute consultation with a certified genetic counselor to review their family history in detail. This is in addition to the extensive family history questionnaire completed by all donors. This consultation often reveals new or more complete information, allowing us to request clarification and in some cases recommend additional genetic screening or review of medical records. It is important to note that the vast majority of concerns uncovered by a thorough family history are NOT detected by carrier screening alone. This comprehensive family history review is a unique service that is not offered by most egg donor agencies.
Surrogacy + Genomics
Surrogates and intended parents have the same hope:
a healthy baby.
At ORM we use reproductive genomics to help our future families achieve that goal. Prior to embryo creation, we offer carrier testing and family history evaluations on egg and sperm providers to identify areas of known risk. After embryo creation, most of our patients also choose to do genetic screening of the embryos via comprehensive chromosome screening (CCS).
Our goal is to reduce known genetic risks prior to transfer to decrease the chance of a surrogate or the intended parents learning unanticipated information later—and to minimize the need for additional genetic during pregnancy. While no amount of preparatory testing can eliminate the small risk of a genetic problem occurring in pregnancy, our goal is to provide the best chance for a smooth, safe and healthy pregnancy for all.
We also understand that surrogates are often not informed about the type and limitations of screening that was done on the intended parents and embryos. We are happy to provide this important education and to interface with prenatal providers as needed.